Heart transplantation at the Institute of Clinical and Experimental Medicine in Prague

In the Institute of Clinical and Experimental Medicine in Prague 101 orthotopic allotransplantations of the heart were performed in 100 patients (87 men and 13 women). The reason for transplantation were terminal stages in the first place dilated cardiomyopathies and ischaemic heart disease. 58% of...

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Bibliographic Details
Published inVnitřní lékar̆stvĭ Vol. 40; no. 2; p. 75
Main Authors Urbanová, D, Málek, I, Gebauerová, M, Stanĕk, V
Format Journal Article
LanguageCzech
Published Czech Republic 01.02.1994
Subjects
Adolescent
Adult
Aged
Child
Czech Republic - epidemiology
Female
Graft Rejection
Heart Transplantation - mortality
Humans
Male
Middle Aged
Czech Republic
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Summary:In the Institute of Clinical and Experimental Medicine in Prague 101 orthotopic allotransplantations of the heart were performed in 100 patients (87 men and 13 women). The reason for transplantation were terminal stages in the first place dilated cardiomyopathies and ischaemic heart disease. 58% of the patients survive after transplantation, the mortality rate is 42%. The highest mortality is in the early postoperative period (within two weeks after operation)--21 cases (50%). The longest survival period is nine years and six months. All patients have cyclosporin immunosuppressive treatment (in combination with another drug, later with another two drugs). In the authors' group in particular incipient acute rejections are encountered, "mild" rejections are less frequent and "moderate" rejections least frequent. The patients do not reach the stage of advanced acute rejection, i.e. "severe" rejection. Acute rejections are treated as a rule with 3 g Urbason. After this treatment acute rejection improves as a rule completely after one or two weeks therapy.
ISSN:0042-773X