Immune system function in the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station

Imbalance was revealed in the proportions of T-lymphocyte subpopulations in those persons engaged in activity in mining employment who had been exposed to a complex of the radiation accident factors. Maximum reduction in the lymphocyte suppressor activity was recordable in those patients in whom the...

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Bibliographic Details
Published inLikars'ka sprava no. 3-4; p. 31
Main Authors Ivanitskaia, N F, Savchenko, M V, Sorokina, S F, Li, Ia B
Format Journal Article
LanguageRussian
Published Ukraine 01.03.1996
Subjects
Adult
Antibody Formation - radiation effects
Humans
Immune System - immunology
Immune System - physiology
Immune System - radiation effects
Immunity, Cellular - radiation effects
Male
Middle Aged
Mining
Occupational Exposure - adverse effects
Power Plants
Radiation Dosage
Radioactive Hazard Release
Ukraine
Ukraine
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Summary:Imbalance was revealed in the proportions of T-lymphocyte subpopulations in those persons engaged in activity in mining employment who had been exposed to a complex of the radiation accident factors. Maximum reduction in the lymphocyte suppressor activity was recordable in those patients in whom the doses of radioactive irradiation received exceeded 25 s Gy. Depression was found of humoral immunity manifested by a drop in the absolute as well as relative numbers of B-lymphocytes and fall in the blood serum levels of Ig G, A. The results of study of clinical-biochemical and immunologic parameters of blood permit individualized therapies be developed, prophylactic measures to be devised to deal with the relevant pathologic processes and conditions in the cohorts examined.
ISSN:1019-5297