Reactivity of hepatitis C virus (HCV) antibody among blood donors in Hungary

The anti-HCV results of 1958 donors are discussed. The Elisa positivity of high risk subjects was as follows: 60% in coagulopathies, 14% in transfused haematological patients and 32% in patients on dialysis. Elisa reactivity of random blood donors was 1.82%, in the group, selected on the basis of tr...

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Bibliographic Details
Published inOrvosi hetilap Vol. 133 Suppl 1; p. 21
Main Authors Héjjas, M, Medgyesi, G, Hajnal, A
Format Journal Article
LanguageHungarian
Published Hungary 05.07.1992
Subjects
Blood Donors
Enzyme-Linked Immunosorbent Assay
Hepacivirus - immunology
Hepatitis Antibodies - immunology
Hepatitis C - enzymology
Hepatitis C - immunology
Hepatitis C - transmission
Humans
Hungary
Mass Screening - legislation & jurisprudence
Hungary
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Summary:The anti-HCV results of 1958 donors are discussed. The Elisa positivity of high risk subjects was as follows: 60% in coagulopathies, 14% in transfused haematological patients and 32% in patients on dialysis. Elisa reactivity of random blood donors was 1.82%, in the group, selected on the basis of transaminase positivity it was over 8%. The confirmed results were compared by the commercially available Elisa tests. 30 positive samples were confirmed by RIBA or Abbott confirmation assay. 35 of the 55 anti-HCV positives were reactive by all the Elisa, 19 samples could be confirmed, 25 were not subjected to any confirmatory assay. Further studies, and the introduction of mandatory screening of blood donors for anti-HCV are necessary.
ISSN:0030-6002