An experimental study of tumor-tropic properties of radionuclide-labeled liposomes

• Published in: Meditsinskaia radiologiia Vol. 36; no. 9; p. 39
• Main Authors: Kostenikov, N A, Fadeev, N P, Serzhanina, V A, Korsakova, L N, Rozenberg, O A
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 1991
• Subjects: Animals; Gallium Radioisotopes - administration & dosage; Liposomes; Lymphoma, Non-Hodgkin - diagnostic imaging; Male; Radionuclide Imaging; Rats; Sarcoma, Experimental - diagnostic imaging; Technetium - administration & dosage

The paper is concerned with the results of experimental investigations to develop methods for obtaining 99mTc and 67Ga-labeled liposomes, possessing tumor-tropic properties. Sphingomyelin vesiculae, labeled with 67Ga with the help of bifunctional chelates, were shown to possess a high level of hyper...