Cell proliferation kinetics in the regenerating rat liver based on flow cytophotometric data

Redistribution of cells according to the ploidy levels permits studying kinetics of cell transitions from the state of mitotic rest to proliferation during the organ regeneration. In the first generation cycle about 95% of cells which accepted a proliferative stimulus leave the G0-phase and then, ha...

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Bibliographic Details
Published inTSitologiia i genetika Vol. 18; no. 4; p. 256
Main Authors Gil'iano, N Ia, Malinovskiĭ, O V
Format Journal Article
LanguageRussian
Published Ukraine 01.07.1984
Subjects
Animals
Autoradiography
Cell Division
DNA - analysis
Flow Cytometry
Hepatectomy
Kinetics
Liver Regeneration
Male
Rats
Time Factors
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Summary:Redistribution of cells according to the ploidy levels permits studying kinetics of cell transitions from the state of mitotic rest to proliferation during the organ regeneration. In the first generation cycle about 95% of cells which accepted a proliferative stimulus leave the G0-phase and then, having completed DNA synthesis, some of them enter mitosis and some are blocked in the G2 phase. About 20% of cells which divide during the second mitosis are the "G2-population" formed after the first cycle.
ISSN:0564-3783