Mitral valve replacement with porcine bioprosthesis in children. Evaluation of 29 patients during 12 years

To analyze the clinical result of the mitral valve substitution for the porcine bioprostheses, the incidence of dysfunction caused by calcification and its importance related to the durability of bioprostheses and also the patients' survival. Twenty-nine children of about seven to sixteen years...

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Bibliographic Details
Published inArquivos brasileiros de cardiologia Vol. 58; no. 2; p. 101
Main Authors Gandra, S M, Rivetti, L A, Pinto, A M, Marinelli, I, Campagnucci, V P, Franken, R A
Format Journal Article
LanguagePortuguese
Published Brazil 01.02.1992
Subjects
Actuarial Analysis
Adolescent
Bioprosthesis
Child
Female
Follow-Up Studies
Heart Valve Diseases - surgery
Heart Valve Prosthesis - mortality
Humans
Male
Mitral Valve - surgery
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Summary:To analyze the clinical result of the mitral valve substitution for the porcine bioprostheses, the incidence of dysfunction caused by calcification and its importance related to the durability of bioprostheses and also the patients' survival. Twenty-nine children of about seven to sixteen years old were operated on from November 1977 to August 1982 and all of them received porcine bioprostheses of low profile. There were three (10.34%) hospital deaths and nine other late mortalities. The follow-up period varied from 4 to 128 months with average of 58.17 months and with the loss of nine patients. An actuarial survival rate of 46.08% has been observed at 11 years after surgery. Calcification of 21 bioprostheses occurred in 14 out of 17 follow-up patients; 47.6% of them happened until the third year of pos-operative and 85.7% until the fifth year. Eleven patients were reoperated on with 9.09% of hospital mortality. There were no cases of thromboembolism. Porcine bioprostheses works well with an evident clinical improvement of patients, with no thromboembolic accidents. However, its durability has been affected by the high incidence of calcification, which is responsible for an increase in late morbidity and mortality. Mitral valve disease treatment in children must be conservative, in an attempt to solve the problem with the different available plastic technics and leave the valve substitution to be a last option. In that case, the preference is given to the homologous bioprostheses.
ISSN:0066-782X