Amino acid pattern variation in animals after the administration of hypocaloric peripheral parenteral nutrition

The pattern of intracellular aminoacids may be reproduced individually and is different for each illness. This study seeks to measure alterations in this pattern in rats after the administration of hypocaloric peripheral parenteral nutrition (HPPN), group B, for five days, by comparing them with rat...

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Published inNutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral Vol. 11; no. 3; pp. 178 - 184
Main Authors de la Hoz Riesco, M L, Prieto Prado, M, García Vielba, J, García Díez, F, García Arumi, E, Culebras Fernández, J M
Format Journal Article
LanguageSpanish
Published Spain 01.05.1996
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Summary:The pattern of intracellular aminoacids may be reproduced individually and is different for each illness. This study seeks to measure alterations in this pattern in rats after the administration of hypocaloric peripheral parenteral nutrition (HPPN), group B, for five days, by comparing them with rats subjected to conventional fluidtherapy, group A, for the same period. HPPN tolerance was good in all cases. Our results show a higher tendency to glyconeogenesis in group A, measured by a reduction in the glycogenic aminoacids especially alanine. An increase in branched aminoacids was observed in group A due to an increase in proteolisis. The animals in group B showed a lesser reduction in the intracellular aminoacids necessary for glyconeogenesis, especially glycine. HPPN, was found, to alter the aminoacids pattern in fasting rats. The results might be corroborated in humans studies.
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ISSN:0212-1611