Features of DNA repair during chronic exposure to mutagenic factors

Long-time in vivo influence of chemical mutagens in low doses can decrease the level of unscheduled DNA synthesis (UDS) induced in human as well as in laboratory mammals. The phenomenon under investigation is not specific neither for chronically acting mutagens nor for challenging agent. A decrease...

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Bibliographic Details
Published inRadiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a Vol. 37; no. 4; p. 565
Main Authors Semov, A B, Ptitsina, S N, Semova, N Iu
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1997
Subjects
Animals
DNA Repair
Gamma Rays
Humans
Mutagens - toxicity
Power Plants
Radioactive Hazard Release
Time Factors
Ukraine
Ultraviolet Rays
Ukraine
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Summary:Long-time in vivo influence of chemical mutagens in low doses can decrease the level of unscheduled DNA synthesis (UDS) induced in human as well as in laboratory mammals. The phenomenon under investigation is not specific neither for chronically acting mutagens nor for challenging agent. A decrease in UV- and gamma-ray-induced UDS was registered after chronic irradiation in plant populations and also in Chernobyl ameliorators and inhabitants of radioactively contaminated regions. The observed effect seems to have general biological character.
ISSN:0869-8031