Must renal biopsy be still performed in "lipoid nephrosis"? (author's transl)

In 52 out of 272 children with one of the following diseases: nephrotic or nephritic syndrome, persistent humaturia and/or proteinuria, renal biopsy was performed on the basis of commonly accepted indications. 18 biopsies were from patients with a clinical picture of lipoid nephrosis and clinical co...

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Bibliographic Details
Published inLa Pediatria medica e chirurgica Vol. 3; no. 5; p. 399
Main Authors Del Gado, R, Polito, C, Strano, C G, Di Toro, R
Format Journal Article
LanguageItalian
Published Italy 01.09.1981
Subjects
Biopsy
Hematuria - diagnosis
Humans
Infant
Kidney - pathology
Nephritis - diagnosis
Nephrosis, Lipoid - diagnosis
Nephrotic Syndrome - diagnosis
Proteinuria - diagnosis
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Summary:In 52 out of 272 children with one of the following diseases: nephrotic or nephritic syndrome, persistent humaturia and/or proteinuria, renal biopsy was performed on the basis of commonly accepted indications. 18 biopsies were from patients with a clinical picture of lipoid nephrosis and clinical course of "non responders" or "frequent relapsers" types. All of them showed the histologic pattern of minimal changes and had a value of Y index according to ISKCD greater than 0,85. Moreover all patients with minimal changes nephrotic syndrome had a Y index greater than 0.85. If these observations will be confirmed renal biopsy would not later be indicated in children with "lipoid nephrosis".
ISSN:0391-5387