Usefulness of long-term follow-up of gastric ulcer: a case load contribution to the natural history of gastric ulcer in relation to treatment with H2-blockaders

Thorough long-term clinical, endoscopic and biopsy follow-up (from 6 months to greater than 8 years; mean follow-up: 3 years 3 months) of a group of 202 cases of apparently benign gastric ulcer has enabled us to evaluate the natural history of gastric ulcer in relation to medical therapy with H2-blo...

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Bibliographic Details
Published inChirurgia italiana Vol. 41; no. 1; p. 22
Main Authors De Bernardin, M, Bortolozzi, E, Danieli, F, Sicari, U, Pinto, G, Gatto, F, Bragato, N, Corso, G F
Format Journal Article
LanguageItalian
Published Italy 01.02.1989
Subjects
Adult
Aged
Aged, 80 and over
Anti-Ulcer Agents - therapeutic use
Biopsy
Evaluation Studies as Topic
Female
Follow-Up Studies
Gastroscopy
Histamine H2 Antagonists - therapeutic use
Humans
Male
Middle Aged
Retrospective Studies
Stomach Ulcer - drug therapy
Stomach Ulcer - pathology
Time Factors
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Summary:Thorough long-term clinical, endoscopic and biopsy follow-up (from 6 months to greater than 8 years; mean follow-up: 3 years 3 months) of a group of 202 cases of apparently benign gastric ulcer has enabled us to evaluate the natural history of gastric ulcer in relation to medical therapy with H2-blockers and to patient compliance when using such drugs. The results confirm the efficacy of H2-antagonist therapy in gastric ulcer healing and in the prevention of relapse. Thorough follow-up, moreover, made it possible to keep surgical operations for non-neoplastic causes down to very low numbers, only 3 patients (1.5%) being operated on for haemorrhagic emergencies and 12 (6%) for non-response to therapy.
ISSN:0009-4773