Steroid hormone receptors and cellular proliferative activity following the short-term use of tamoxifen and chlorotrianisene in breast cancer

• Published in: Eksperimentalʹnaja onkologija Vol. 7; no. 5; p. 66
• Main Authors: Vyshinskaia, G V, Murav'eva, N I, Shelsputina, Z F, Kuz'mina, Z V, Nikolaeva, T G
• Format: Journal Article
• Language: Russian
• Published: Ukraine 1985
• Subjects: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Breast Neoplasms - analysis; Breast Neoplasms - drug therapy; Cell Transformation, Neoplastic - drug effects; Chlorotrianisene - therapeutic use; DNA, Neoplasm - biosynthesis; Female; Humans; Middle Aged; Receptors, Estrogen - analysis; Receptors, Estrogen - drug effects; Receptors, Progesterone - analysis; Receptors, Progesterone - drug effects; Tamoxifen - therapeutic use; Time Factors

The content of estrogen receptors (ER), progesterone receptors (PR), the proliferative pool level in the tumour tissue were investigated in 6 patients with the disseminated breast tumour before and after 9-day treatment with tamoxifen and chlorotrianisene for intensification of the effect of cytosta...