Proliferative activity of the hematopoietic stem cell in antigenically stimulated splenectomized mice

Proliferative activity of hemopoietic bone-marrow stem cells has been studied in splenectomized mice in response to sheep red blood cells (2 X 10(8], pneumococcal polysaccharide (100 micrograms) and lipopolysaccharide E. coli (100 micrograms) injections. Spleen and its lymphoid cellular elements wer...

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Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 104; no. 7; p. 91
Main Authors Gaĭdul', K V, Tsyrlova, I G, Kozlov, V A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1987
Subjects
Animals
Antigens - immunology
Bone Marrow Cells
Cell Division
Colony-Forming Units Assay
Erythrocytes - immunology
Escherichia coli - immunology
Hematopoietic Stem Cells - cytology
Hematopoietic Stem Cells - immunology
Lipopolysaccharides - immunology
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Polysaccharides, Bacterial - immunology
Spleen - cytology
Spleen - immunology
Splenectomy
Streptococcus pneumoniae - immunology
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Summary:Proliferative activity of hemopoietic bone-marrow stem cells has been studied in splenectomized mice in response to sheep red blood cells (2 X 10(8], pneumococcal polysaccharide (100 micrograms) and lipopolysaccharide E. coli (100 micrograms) injections. Spleen and its lymphoid cellular elements were shown to be of great importance for the regulation of the functional activity of hemopoietic stem cells under the antigenic influence.
ISSN:0365-9615