What is the role of sensitization in uremic pruritus? An allergologic study

Patch tests were carried out to evaluate the presence of a sensitization to some components of dialytic circuits in 17 uremic patients complaining of pruritus of unknown origin. Fragments of different dialyzer membranes, of tubing sets, of dialyzer membranes recently resterilized with ethylene oxide...

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Bibliographic Details
Published inNephron (2015) Vol. 57; no. 3; p. 319
Main Authors Rollino, C, Goitre, M, Piccoli, G, Puiatti, P, Martina, G, Formica, M, Quarello, F, Bernengo, M G
Format Journal Article
LanguageEnglish
Published Switzerland 1991
Subjects
Adult
Aged
Female
Humans
Hypersensitivity, Delayed
Male
Membranes, Artificial
Middle Aged
Pruritus - etiology
Pruritus - immunology
Renal Dialysis - adverse effects
Skin Tests
Uremia - complications
Uremia - immunology
Uremia - therapy
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Summary:Patch tests were carried out to evaluate the presence of a sensitization to some components of dialytic circuits in 17 uremic patients complaining of pruritus of unknown origin. Fragments of different dialyzer membranes, of tubing sets, of dialyzer membranes recently resterilized with ethylene oxide and the International Contact Dermatitis Research Group standard series substances were tested. Neither patients nor healthy subjects reacted positively to patch tests, which leads us to question the role of contact allergy in the determination of uremic pruritus.
ISSN:1660-8151