Families with 2 oligophrenic siblings

Under observation there were 27 families with two mentally deranged sibs in each born by intellectually normal parents. In 2 of 24 families, the clinical picture of the derangement in the sibs was different, and in the rest of 22 identical. In 3 families, a sex-linked recessive oligophrenia with a n...

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Bibliographic Details
Published inZhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) Vol. 81; no. 3; p. 383
Main Author Marincheva, G S
Format Journal Article
LanguageRussian
Published Russia (Federation) 1981
Subjects
Abnormalities, Multiple - complications
Brain Diseases - complications
Cerebral Palsy - complications
Consanguinity
Female
Genes, Recessive
Humans
Intellectual Disability - complications
Intellectual Disability - genetics
Male
X Chromosome
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Summary:Under observation there were 27 families with two mentally deranged sibs in each born by intellectually normal parents. In 2 of 24 families, the clinical picture of the derangement in the sibs was different, and in the rest of 22 identical. In 3 families, a sex-linked recessive oligophrenia with a nonspecific clinical picture was diagnosed. Prevalent were clinically non-differentiated forms of the oligophrenia. In 2 families, the oligophrenia was combined with clinical signs of hereditary defects of metabolism. Parents' consanguinity was registered in 4 families.
ISSN:0044-4588