Surgical treatment of myasthenia gravis in children

Thymectomy was included in the complex of therapeutic measures in the management of generalized myasthenia in 41 children. Much attention was given to preoperative management in which plasmapheresis was applied along with the traditional methods. As a result, maximum compensation of the myasthenic d...

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Published inGrudnaia i serdechno-sosudistaia khirurgiia no. 10; p. 68
Main Authors Tsuman, V G, Odinokova, V A, Agafonov, B V, Nalivkin, A E, Gurevich, L E, Sidorova, O P, Cherkesova, Z I, Fialkovskiĭ, S Iu
Format Journal Article
LanguageRussian
Published Russia (Federation) 1990
Subjects
Adolescent
Child
Female
Humans
Hyperplasia
Male
Myasthenia Gravis - pathology
Myasthenia Gravis - surgery
Plasmapheresis
Preoperative Care
Thymectomy
Thymus Gland - pathology
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Summary:Thymectomy was included in the complex of therapeutic measures in the management of generalized myasthenia in 41 children. Much attention was given to preoperative management in which plasmapheresis was applied along with the traditional methods. As a result, maximum compensation of the myasthenic disorders was achieved and spontaneous respiration was restored in 9 patients who were given artificial ventilation of the lungs before the operation. The authors describe the techniques of thymectomy and the changes found in the thymus during histological study. No complications occurred. All of the children were discharged from the clinic in an improved condition. The late-term results were studied in 38 children in follow-up periods of 6 months to 4 years. Marked stable improvement was recorded in 31 (77.5%) patients.
ISSN:0236-2791