Successful treatment of autoimmune hemolytic anemia with cyclosporin A

A sixty-year-old patient suffering from an idiopathic immunohemolytic anemia was treated by 3 plasma exchanges (with 31 exchange-volume) and following by Ciclosporin A (3 mg/kg body weight) after the monotherapy of prednisone has been unsuccessful. Ciclosporin A promptly effected a continuous remiss...

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Bibliographic Details
Published inWiener medizinische Wochenschrift Vol. 136; no. 21-22; p. 567
Main Authors Pogglitsch, H, Warnkross, H, Weinrauch, V, Winkler, H M
Format Journal Article
LanguageGerman
Published Austria 30.11.1986
Subjects
Anemia, Hemolytic, Autoimmune - drug therapy
Blood Transfusion
Combined Modality Therapy
Cyclosporins - therapeutic use
Dose-Response Relationship, Drug
Erythrocyte Transfusion
Female
Humans
Middle Aged
Nephrosis, Lipoid - drug therapy
Plasma Exchange
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Summary:A sixty-year-old patient suffering from an idiopathic immunohemolytic anemia was treated by 3 plasma exchanges (with 31 exchange-volume) and following by Ciclosporin A (3 mg/kg body weight) after the monotherapy of prednisone has been unsuccessful. Ciclosporin A promptly effected a continuous remission of the autoimmune hemolysis. The mode of action of Ciclosporin A in immunhemolytic anemia depending on incomplete warm-auto-antibodies is discussed.
ISSN:0043-5341