The detection of metastases of ovarian carcinoma by immunoscintigraphy with monoclonal antibodies

Sixty eight women, operated for ovarian carcinoma, were studied by monoclonal antibodies anti-CA-125 labeled with 131I. 99m-Tc was used for the scintigraphy. Ninety-one metastases were discovered as 73 of them were established surgically. 52/61 were confirmed in the pelvis, 19/24 in the abdominal ca...

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Bibliographic Details
Published inAkusherstvo i ginekologiia Vol. 29; no. 1; p. 57
Main Authors Peking, A, Marinov, V
Format Journal Article
LanguageBulgarian
Published Bulgaria 1990
Subjects
Adult
Antibodies, Monoclonal
Antigens, Tumor-Associated, Carbohydrate - immunology
Carcinoma - diagnostic imaging
Evaluation Studies as Topic
Female
Humans
Iodine Radioisotopes
Lymphatic Metastasis
Middle Aged
Ovarian Neoplasms - diagnostic imaging
Radionuclide Imaging
Sodium Pertechnetate Tc 99m
Technetium Tc 99m Aggregated Albumin
Tomography, X-Ray Computed
Ultrasonography
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Summary:Sixty eight women, operated for ovarian carcinoma, were studied by monoclonal antibodies anti-CA-125 labeled with 131I. 99m-Tc was used for the scintigraphy. Ninety-one metastases were discovered as 73 of them were established surgically. 52/61 were confirmed in the pelvis, 19/24 in the abdominal cavity and 3/6 in the liver. Higher precision of immunoscintigraphy was found in the diagnosis of liver metastasis, when it was compared with echographic and computed tomographic examinations.
ISSN:0324-0959