Stability and chemosensitivity of Plasmodium falciparum to chloroquine in 1990 and 1991 in Ankazobe, a village in high plateau Madagascar

The in vivo and in vitro response of Plasmodium falciparum to chloroquine was conducted in Ankazobe, a village located in the high plateau area. These studies confirmed the low level of chloroquine-resistance. The in vivo data indicate the absence of increase resistance during the 2 years study. Chl...

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Published inBulletin de la Societe de pathologie exotique (1990) Vol. 85; no. 3; pp. 219 - 22; discussion 222-3
Main Authors Ringwald, P, Rabarison, P, Raharimalala, L, Rason, M D, Lepers, J P, Le Bras, J, Roux, J
Format Journal Article
LanguageFrench
Published France 1992
Subjects
Animals
Chloroquine - pharmacology
Chloroquine - therapeutic use
Drug Resistance
Humans
Madagascar
Malaria, Falciparum - drug therapy
Malaria, Falciparum - parasitology
Plasmodium falciparum - drug effects
Madagascar
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Summary:The in vivo and in vitro response of Plasmodium falciparum to chloroquine was conducted in Ankazobe, a village located in the high plateau area. These studies confirmed the low level of chloroquine-resistance. The in vivo data indicate the absence of increase resistance during the 2 years study. Chloroquine is still the drug of choice for the treatment of malaria attack in this area.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0037-9085