Barrett's esophagus does not revert after medical or surgical therapy for gastroesophageal reflux

An evaluation was made of 34 patients having Barrett's oesophagus. Medical therapy consisted of antacids, H2 blockers, orthopramides, and postural measures (20 cases, mean follow-up 2.9 years). A Nissen fundoplication was done in 14 cases (mean follow-up 2.5 years). Clinical, endoscopic and his...

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Bibliographic Details
Published inRevista española de enfermedades digestivas Vol. 79; no. 2; p. 89
Main Authors Ortiz, A, Aguayo, J L, Parrilla, P, Martínez de Haro, L, Morales Cuenca, G, García Marcilla, J A, Bermejo, J, Molina, J
Format Journal Article
LanguageSpanish
Published Spain 01.02.1991
Subjects
Adolescent
Adult
Aged
Barrett Esophagus - etiology
Barrett Esophagus - therapy
Child
Esophagitis, Peptic - complications
Esophagitis, Peptic - therapy
Female
Humans
Male
Middle Aged
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Summary:An evaluation was made of 34 patients having Barrett's oesophagus. Medical therapy consisted of antacids, H2 blockers, orthopramides, and postural measures (20 cases, mean follow-up 2.9 years). A Nissen fundoplication was done in 14 cases (mean follow-up 2.5 years). Clinical, endoscopic and histologic evaluation was done in all patients and pH measurements also done in all operated cases. Clinical results have been excellent in 70% of medically treated patients and in 100% of surgically treated ones, pH measurements were between normal limits in all operated patients. However, recovery of the normal epithelium did not occur in any case, except for some partial improvement in one patient treated surgically.
ISSN:1130-0108