Characteristics of the spontaneous humoral immunity reactions to collagen type I in systemic lupus erythematosus patients

A study of the state of the humoral immunity in 36 SLE patients made it possible to detect an increase in the level of autoantibodies to type I collagen in comparison to the level of autoantibodies in healthy donors. It showed correlation with the activity of a process, its course, clinical signs of...

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Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 58; no. 12; p. 84
Main Authors Nesvizhskiĭ, Iu V, Solov'ev, S K, Panasiuk, A F
Format Journal Article
LanguageRussian
Published Russia (Federation) 1986
Subjects
Adolescent
Adult
Antibody Formation
Autoantibodies - analysis
Chronic Disease
Collagen - immunology
Female
Humans
Lupus Erythematosus, Systemic - immunology
Lupus Nephritis - immunology
Male
Middle Aged
Raynaud Disease - immunology
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Summary:A study of the state of the humoral immunity in 36 SLE patients made it possible to detect an increase in the level of autoantibodies to type I collagen in comparison to the level of autoantibodies in healthy donors. It showed correlation with the activity of a process, its course, clinical signs of disease, progression of renal pathology and the levels of antinuclear factor and gamma globulins.
ISSN:0040-3660