Hyperlactacidemia in intestinal ischemia. I. Theoretical considerations

Acute interruption of the blood flow of the bowel is a very severe disease. The very high lethality mainly depends on the difficulties in diagnosis. Laboratory findings were not considered until now. Earlier investigations have demonstrated the bowel's high demand for blood and oxygen and a spe...

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Bibliographic Details
Published inLangenbecks Archiv für Chirurgie Vol. 370; no. 2; p. 63
Main Authors Nutz, V, Sommer, H J
Format Journal Article
LanguageGerman
Published Germany 1987
Subjects
Animals
Humans
Intestines - blood supply
Ischemia - blood
Lactates - blood
Lactic Acid
Mesenteric Vascular Occlusion - blood
Regional Blood Flow
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Summary:Acute interruption of the blood flow of the bowel is a very severe disease. The very high lethality mainly depends on the difficulties in diagnosis. Laboratory findings were not considered until now. Earlier investigations have demonstrated the bowel's high demand for blood and oxygen and a specific high vulnerability by ischemia. Therefore anaerobic metabolism of the bowel should cause a high lactacidemia, even before necrosis.
ISSN:0023-8236