Cytophotometric and electron microscopic studies of chronic human skin lymphomas. II. Research on lymph node involvement
Results of electron microscopic and cytophotometric studies of biopsy material from lymph nodes of patients with cutaneous lymphomas with low degree of malignancy are discussed, with special reference to early diagnostic criteria of the disease. Specific characteristics of tumor tissue involve the p...
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Published in | T͡S︡itologii͡a Vol. 29; no. 4; p. 421 |
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Main Authors | , , , , |
Format | Journal Article |
Language | Russian |
Published |
Russia (Federation)
01.04.1987
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Subjects | |
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Abstract | Results of electron microscopic and cytophotometric studies of biopsy material from lymph nodes of patients with cutaneous lymphomas with low degree of malignancy are discussed, with special reference to early diagnostic criteria of the disease. Specific characteristics of tumor tissue involve the presence of atypical lymphocytes with marginal condensed chromatin extrusions of nuclear material, deep invaginations of the nuclear membrane, nuclear pockets, excess of the mean DNA content per nucleus above the diploid standard level, more than 5% of nuclei being in the hyperdiploid area. Electron microscopic and cytophotometric methods allowed to diagnose the tumor injury of lymph nodes, when the traditional histological techniques revealed no signs of malignancy. |
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AbstractList | Results of electron microscopic and cytophotometric studies of biopsy material from lymph nodes of patients with cutaneous lymphomas with low degree of malignancy are discussed, with special reference to early diagnostic criteria of the disease. Specific characteristics of tumor tissue involve the presence of atypical lymphocytes with marginal condensed chromatin extrusions of nuclear material, deep invaginations of the nuclear membrane, nuclear pockets, excess of the mean DNA content per nucleus above the diploid standard level, more than 5% of nuclei being in the hyperdiploid area. Electron microscopic and cytophotometric methods allowed to diagnose the tumor injury of lymph nodes, when the traditional histological techniques revealed no signs of malignancy. |
Author | Selivanova, G V Raznatovskiĭ, I M Bushmarina, M S Bogdanova, M S Rodionov, A N |
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SubjectTerms | Biopsy Cytophotometry DNA - analysis DNA, Neoplasm - analysis Humans Lymph Nodes - analysis Lymph Nodes - ultrastructure Lymphadenitis - metabolism Lymphadenitis - pathology Lymphatic Metastasis Lymphocytes - analysis Lymphoma - analysis Lymphoma - ultrastructure Microscopy, Electron Skin Neoplasms - analysis Skin Neoplasms - ultrastructure |
Title | Cytophotometric and electron microscopic studies of chronic human skin lymphomas. II. Research on lymph node involvement |
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