Cytophotometric and electron microscopic studies of chronic human skin lymphomas. II. Research on lymph node involvement

Results of electron microscopic and cytophotometric studies of biopsy material from lymph nodes of patients with cutaneous lymphomas with low degree of malignancy are discussed, with special reference to early diagnostic criteria of the disease. Specific characteristics of tumor tissue involve the p...

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Bibliographic Details
Published inT͡S︡itologii͡a Vol. 29; no. 4; p. 421
Main Authors Bushmarina, M S, Bogdanova, M S, Selivanova, G V, Rodionov, A N, Raznatovskiĭ, I M
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.04.1987
Subjects
Biopsy
Cytophotometry
DNA - analysis
DNA, Neoplasm - analysis
Humans
Lymph Nodes - analysis
Lymph Nodes - ultrastructure
Lymphadenitis - metabolism
Lymphadenitis - pathology
Lymphatic Metastasis
Lymphocytes - analysis
Lymphoma - analysis
Lymphoma - ultrastructure
Microscopy, Electron
Skin Neoplasms - analysis
Skin Neoplasms - ultrastructure
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Summary:Results of electron microscopic and cytophotometric studies of biopsy material from lymph nodes of patients with cutaneous lymphomas with low degree of malignancy are discussed, with special reference to early diagnostic criteria of the disease. Specific characteristics of tumor tissue involve the presence of atypical lymphocytes with marginal condensed chromatin extrusions of nuclear material, deep invaginations of the nuclear membrane, nuclear pockets, excess of the mean DNA content per nucleus above the diploid standard level, more than 5% of nuclei being in the hyperdiploid area. Electron microscopic and cytophotometric methods allowed to diagnose the tumor injury of lymph nodes, when the traditional histological techniques revealed no signs of malignancy.
ISSN:0041-3771