Action of cortical extracts of the left and right hemispheres on the recovery of conditioned reflex activity in rats after unilateral removal of the frontal cortex

The recovery of active avoidance conditioned reflex (AACR) was investigated after unilateral frontal cortex extirpation. Intraperitoneal injection of extracts from left or right brain cortex (1 mg/kg) of healthy rats (LE or RE) stimulated AACR recovery in animals with lobectomy on the same side. If...

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Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 105; no. 3; p. 267
Main Authors Kryzhanovskiĭ, G N, Romanova, G A, Sovetov, A N, Lutsenko, V K, Karganov, M Iu
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.03.1988
Subjects
Animals
Cerebral Cortex - physiology
Conditioning, Classical - drug effects
Conditioning, Classical - physiology
Dominance, Cerebral - drug effects
Dominance, Cerebral - physiology
Electric Stimulation
Escape Reaction - drug effects
Escape Reaction - physiology
Frontal Lobe - physiology
Frontal Lobe - surgery
Molecular Weight
Photic Stimulation
Rats
Time Factors
Tissue Extracts - pharmacology
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Summary:The recovery of active avoidance conditioned reflex (AACR) was investigated after unilateral frontal cortex extirpation. Intraperitoneal injection of extracts from left or right brain cortex (1 mg/kg) of healthy rats (LE or RE) stimulated AACR recovery in animals with lobectomy on the same side. If RE was extracted 9 days after left side brain extirpation, i.e. during the period of the development of compensatory processes, its effect on AACR recovery was stronger in left-operated animals, while in right-operated animals it remained unchanged.
ISSN:0365-9615