Periodic disease and pregnancy

The authors report a case of familial Mediterranean fever in a pregnant woman treated with Colchicine. She delivered normally at term. A review of the literature shows that colchicine does not have a teratogenic effect which it was long thought to have. All the same it is best to carry out fetal kar...

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Bibliographic Details
Published inJournal de gynécologie, obstétrique et biologie de la reproduction Vol. 20; no. 4; p. 554
Main Authors Cousin, C, Palaric, J C, Jacquemard, F, Lucas, J, Giraud, J R
Format Journal Article
LanguageFrench
Published France 1991
Subjects
Adult
Clinical Protocols
Colchicine - administration & dosage
Colchicine - pharmacology
Colchicine - therapeutic use
Familial Mediterranean Fever - drug therapy
Familial Mediterranean Fever - genetics
Familial Mediterranean Fever - physiopathology
Female
Humans
Menstrual Cycle
Pregnancy
Pregnancy Complications - drug therapy
Pregnancy Complications - physiopathology
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Summary:The authors report a case of familial Mediterranean fever in a pregnant woman treated with Colchicine. She delivered normally at term. A review of the literature shows that colchicine does not have a teratogenic effect which it was long thought to have. All the same it is best to carry out fetal karyotype examination using early amniocentesis. Furthermore, colchicine improves fertility which is disturbed in these patients and pregnancy has a good effect on the disease.
ISSN:0368-2315