Magnetization transfer MR of cerebrovascular disorders using calculated images

This study applied a magnetization transfer contrast method to patients with cerebrovascular disorders. A 1.5T superconducting MR unit was used, and magnetization transfer ratio (MTR) images were calculated by evaluating two paired images before and after off-resonance gradient echo pulse sequences....

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Bibliographic Details
Published inNihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica Vol. 57; no. 7; p. 402
Main Authors Enomoto, K, Watabe, T, Amanuma, M, Heshiki, A
Format Journal Article
LanguageJapanese
Published Japan 01.06.1997
Subjects
Adolescent
Adult
Aged
Brain - pathology
Cerebrovascular Disorders - diagnosis
Cerebrovascular Disorders - pathology
Child
Child, Preschool
Female
Humans
Image Enhancement - methods
Infant
Magnetic Resonance Imaging - methods
Male
Middle Aged
Time Factors
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Summary:This study applied a magnetization transfer contrast method to patients with cerebrovascular disorders. A 1.5T superconducting MR unit was used, and magnetization transfer ratio (MTR) images were calculated by evaluating two paired images before and after off-resonance gradient echo pulse sequences. The normal white matter showed the highest MTRs, CSF the lowest, and gray matter, intermediate. Cerebral ischemic patients showed two patterns according to the chronological stage of the affected area. Lesions in the acute and subacute stages revealed higher transfer rates than those in the chronic stage. Patients with cerebral hemorrhage were divided into three groups: the hyperacute group showed a low transfer pattern; the acute group presented inhomogeneous high transfer rates; and the subacute group showed remarkably low transfer rates. In the acute and subacute ischemic stages, increased macromolecules caused higher MTRs than in the chronic stage. In hemorrhagic groups, low MTRs in subacute hemorrhage reflected the transfer of methemoglobin. High MTRs in acute hemorrhage with rich deoxyhemoglobin suggested increased fibrin, plasma, and serum components of macromolecules. The MTC method provided new chronological information on cerebral hemorrhage, adding to that provided by routine MR images.
ISSN:0048-0428