Argentinian collaborative study on prevalence of erythromycin and penicillin susceptibility in Streptococcus pyogenes. The Argentinian Streptococcus Study Group

• Published in: Diagnostic microbiology and infectious disease Vol. 29; no. 1; pp. 29 - 32
• Main Authors: Lopardo, H A, Venuta, M E, Vidal, P, Rosaenz, L, Corthey, C, Farinati, A, Couto, E, Sarachian, B, Sparo, M, Kaufman, S, De Mier, C A, Gubbay, L, Scilingo, V, Villaverde, P
• Format: Journal Article
• Language: English
• Published: United States 01.09.1997
• Subjects: Anti-Bacterial Agents - pharmacology; Argentina; Drug Resistance, Microbial; Erythromycin - pharmacology; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins - pharmacology; Streptococcus pyogenes - drug effects; Streptococcus pyogenes - metabolism; Argentina
• ISSN: 0732-8893

Two monthly studies on the prevalence of penicillin and erythromycin susceptibility of Streptococcus pyogenes were performed in May and October of 1994 in Argentina. A total of 58 centers from 27 cities participated in these studies. A total of 1072 isolates were tested by a diffusion method, although 595 isolates were tested both by the diffusion and an agar dilution method (n = 1767 isolates). No penicillin-resistant streptococci were found in our study (MIC100 = 0.03 microgram/ml). Only four isolates were confirmed as erythromycin resistant S. pyogenes (prevalence 0.14 and 0.28% in May and October 1994, respectively). Resistance in three isolates was due to an inducible mechanism, although in one strain a different phenotype was observed.