Lipid spectrum of rat liver and brain after administration of pyrazole

The effect of pyrazole (360 mg/kg, intraperitoneally) on the levels of lipid fractions was studied in the rat liver and brain. There were no differences in hepatic lipid levels after administration of pyrazole alone and in combination with ethanol (20% solution, 1 g/ kg body weight, intragastrically...

Full description

Saved in:
Bibliographic Details
Published inPatologicheskaia fiziologiia i eksperimental'naia terapiia no. 1; p. 15
Main Authors Selevich, M I, Larin, F S, Lechevich, V V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.1997
Subjects
Alcohol Dehydrogenase - antagonists & inhibitors
Animals
Brain - drug effects
Brain - metabolism
Enzyme Inhibitors - pharmacology
Lipid Metabolism
Liver - drug effects
Liver - metabolism
Male
Pyrazoles - pharmacology
Rats
Online AccessGet more information

Cover

More Information
Summary:The effect of pyrazole (360 mg/kg, intraperitoneally) on the levels of lipid fractions was studied in the rat liver and brain. There were no differences in hepatic lipid levels after administration of pyrazole alone and in combination with ethanol (20% solution, 1 g/ kg body weight, intragastrically). Pyrazole alone or in combination with alcohol elevates the concentrations of cholesterol, total phospholipids, phosphatidylethanolamine, and cerebrosides III, reduces the levels of sphingomyelin and cardiolipin.
ISSN:0031-2991