The technology for manufacturing antiparasitic preparations. 1. The development of a technology for producing the anthelmintic triklazan in finely dispersed form and the evaluation of its antinematodal, anticestodal and antitrematodal activities

The authors describe the technology of preparing a new anthelmintic agent triclazan, N-(3,4-dichlorophenyl)-2-[(benzo-2,1,3-thiadiazole-4-sulfonyl)amino]-5- chlorobenzamide, finely dispersed (the particles size 4-8 mu). Triclazan is highly effective not only in hymenolepiasis and trichocephaliasis,...

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Published inMeditsinskaia parazitologiia i parazitarnye bolezni no. 5; p. 48
Main Authors Mikhaĭlitsyn, F S, Petrov, Iu F, Smirnov, A A, Drusviatskaia, S K, Aleksandrov, A G, Uvarova, N A, Kazarin, A Iu, Lozlov, V N, Bol'shakova, A Iu
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.10.1993
Subjects
Animals
Anthelmintics - administration & dosage
Anthelmintics - chemical synthesis
Anthelmintics - chemistry
Cestode Infections - drug therapy
Cestode Infections - veterinary
Drug Evaluation, Preclinical
Nematode Infections - drug therapy
Nematode Infections - veterinary
Particle Size
Sheep
Sheep Diseases - drug therapy
Thiadiazoles - administration & dosage
Thiadiazoles - chemical synthesis
Thiadiazoles - chemistry
Trematode Infections - drug therapy
Trematode Infections - veterinary
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Summary:The authors describe the technology of preparing a new anthelmintic agent triclazan, N-(3,4-dichlorophenyl)-2-[(benzo-2,1,3-thiadiazole-4-sulfonyl)amino]-5- chlorobenzamide, finely dispersed (the particles size 4-8 mu). Triclazan is highly effective not only in hymenolepiasis and trichocephaliasis, as was shown previously, but in fascioliasis, monieziasis and intestinal nematodiasis of sheep as well.
ISSN:0025-8326