Cardiogenic shock caused by 5-fluorouracil

The authors report the observation of one patient in whom the first administration of chemotherapy with fluoro-5 uracil has induced a severe but reversible cardiogenic shock. The latter was preceded by a prolonged, constrictive thoracic pain without myocardial infarction constitution. The cardiac to...

Full description

Saved in:
Bibliographic Details
Published inAnnales de cardiologie et d'angéiologie Vol. 39; no. 3; p. 179
Main Authors Mazet, C, Dellinger, A, Vital Durand, D, Adnaoui, M, Fournier, G, Levrat, R
Format Journal Article
LanguageFrench
Published France 01.03.1990
Subjects
Fluorouracil - adverse effects
Humans
Male
Middle Aged
Shock, Cardiogenic - chemically induced
Shock, Cardiogenic - etiology
Online AccessGet more information

Cover

More Information
Summary:The authors report the observation of one patient in whom the first administration of chemotherapy with fluoro-5 uracil has induced a severe but reversible cardiogenic shock. The latter was preceded by a prolonged, constrictive thoracic pain without myocardial infarction constitution. The cardiac toxicity of fluoro-5 uracil has been well described in the form of anginal pains receding with the discontinuation of the treatment. However, the possible occurrence of arrhythmias, of collapse and even sudden deaths leads the authors to suggest the daily clinical and electrical observation of the patients treated with fluoro-5 uractil.
ISSN:0003-3928