Multiple cancers: a case with 5 different tumors

We report the very unusual observation of an 85-year-old woman who developed five different tumors in distinct sites over a 12-year period. These tumors were, in the following order of appearance, an infiltrating lobular carcinoma of the breast, an endometrial carcinoma with an ovarian granulosa cel...

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Bibliographic Details
Published inArchives d'anatomie et de cytologie pathologiques Vol. 37; no. 3; p. 115
Main Authors Seniuta, P, de Mascarel, I, Coindre, J M, Trojani, M
Format Journal Article
LanguageFrench
Published France 1989
Subjects
Adenocarcinoma
Aged
Aged, 80 and over
Breast Neoplasms
Carcinoma
Carcinoma, Transitional Cell
Female
Granulosa Cell Tumor
Humans
Kidney Neoplasms
Neoplasms, Multiple Primary
Ovarian Neoplasms
Urinary Bladder Neoplasms
Uterine Neoplasms
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Summary:We report the very unusual observation of an 85-year-old woman who developed five different tumors in distinct sites over a 12-year period. These tumors were, in the following order of appearance, an infiltrating lobular carcinoma of the breast, an endometrial carcinoma with an ovarian granulosa cell tumor, a clear cell adenocarcinoma of the kidney, and a urothelial carcinoma of the bladder. Two factors may have been involved in the genesis of the multiple carcinomas in this patient, i.e. a hormonal factor (hyperestrogenemia) and radiotherapy.
ISSN:0395-501X