Campylobacter pylori colonization and gastroduodenal pathology

• Published in: Minerva medica Vol. 79; no. 11; p. 957
• Main Authors: Gullini, S, Basso, O, Boccia, S, Macario, F, Cantarini, D, Ghinelli, F
• Format: Journal Article
• Language: Italian
• Published: Italy 01.11.1988
• Subjects: Adult; Aged; Aged, 80 and over; Campylobacter - isolation & purification; Campylobacter Infections - complications; Chronic Disease; Duodenal Diseases - diagnosis; Duodenal Diseases - etiology; Duodenal Ulcer - etiology; Duodenitis - etiology; Endoscopy; Female; Gastric Mucosa - microbiology; Gastritis - etiology; Humans; Male; Middle Aged; Stomach Diseases - diagnosis; Stomach Diseases - etiology; Stomach Ulcer - etiology
• ISSN: 0026-4806

355 patients suffering from dyspepsia with an endoscopic pathological picture were examined. Campylobacter pylori was sought histologically and by culture. Histological and cultural results were compared. There were no bacteria on the gastric mucosa of 46 patients who had no histopathological evidence of lesions. Cultural studies were performed in 40 cases on endoscopic instruments used during the examination, before and after standard sterilization. Campylobacter pylori was found on the gastric mucosa of 224 patients (63.09%); 91.93% with duodenal ulcer; 71.87% with gastric ulcer; 54.23% with erosive duodenitis; 56.71% with erosive gastritis and 54.81% with chronic gastropathy. The agreement between the two techniques was 75.39%, with a male prevalence (p = 0.05). Campylobacter pylori was present on the gastric mucosa of 10.86% of patients without histopathological evidence of lesions. Standard sterilization with alkyl-dimethyl-benzyl ammonium eliminated the campylobacter in 100% of cases.