Changes in the kallikrein-kinin system in chronic hemodialysis patients
The pre-kallikrein values, kallikrein inhibitors and protamine-splitting activity were determined in patients treated by means of chronic haemodialysis. Frequent use of dialysers leads to significant changes in the pre-kallikrein and kallikrein-inhibitor values. On the other hand the pre-kallikrein...
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Published in | Zeitschrift fur Urologie und Nephrologie Vol. 75; no. 2; p. 81 |
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Main Authors | , |
Format | Journal Article |
Language | German |
Published |
Germany
01.02.1982
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Subjects | |
Online Access | Get more information |
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Summary: | The pre-kallikrein values, kallikrein inhibitors and protamine-splitting activity were determined in patients treated by means of chronic haemodialysis. Frequent use of dialysers leads to significant changes in the pre-kallikrein and kallikrein-inhibitor values. On the other hand the pre-kallikrein value remains unchanged after a single use of the capillary kidneys Hemoflow (Fresenius). A much smaller decrease in the kallikrein inhibitor value is observed than after frequent use of dialysers. In all the patients investigated the total protamine-splitting activity remained unchanged. Under these circumstances the inhibition capacity is probably sufficient to guarantee a control with respect to fibrinolysis, blood coagulation and the production of kinine. |
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ISSN: | 0044-3611 |