Burkitt lymphoma in Cameroon children: descriptive and clinico-anatomical aspects

This retrospective study is armed to indicate the descriptive and pathological aspects of children Burkitt lymphoma in Cameroon. It was performed on a 4 year period between July 1988 and July 1992. Children from 0 to 15-year-old who were hospitalized and who had histologically provern Burkitt lympho...

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Bibliographic Details
Published inBulletin du cancer Vol. 84; no. 4; p. 379
Main Authors Doumbé, P, Mbakop, A, Essomba Mboumi, M T, Obama, M T, Kago, I, Gonsu, J, Santiago, M, Tetanye, E
Format Journal Article
LanguageFrench
Published France 01.04.1997
Subjects
Abdominal Neoplasms - blood
Abdominal Neoplasms - epidemiology
Abdominal Neoplasms - immunology
Abdominal Neoplasms - pathology
Adolescent
Animals
Burkitt Lymphoma - blood
Burkitt Lymphoma - epidemiology
Burkitt Lymphoma - immunology
Burkitt Lymphoma - pathology
Cameroon - epidemiology
Child
Child, Preschool
Facial Neoplasms - blood
Facial Neoplasms - epidemiology
Facial Neoplasms - immunology
Facial Neoplasms - pathology
Female
Herpesvirus 4, Human - immunology
Humans
Infant
Male
Maxillary Neoplasms - blood
Maxillary Neoplasms - epidemiology
Maxillary Neoplasms - immunology
Maxillary Neoplasms - pathology
Neoplasm Staging
Plasmodium falciparum
Prognosis
Retrospective Studies
Risk Factors
Cameroon
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Summary:This retrospective study is armed to indicate the descriptive and pathological aspects of children Burkitt lymphoma in Cameroon. It was performed on a 4 year period between July 1988 and July 1992. Children from 0 to 15-year-old who were hospitalized and who had histologically provern Burkitt lymphoma were included. There were 39 patients, that is 27% of all malignant tumors in children during this period. Twenty-four were boys and 15 were girls; the median age was 90 months (+/-46) (range from 3 to 180 months). All children had Plasmodium falciparum infection. EBV serology was positive in 18 patients out of 25 (72%), 14 (36%) had a good nutritional status, the 25 other patients suffered malnutrition. Tumor localizations were: maxillary in 29 (74%) patients, abdominal in 7 (18%), other in 3 patients. Clinical stages according to Murphy classification were: stage I in 6 (15%) patients, II in 3 (8%), III in 20 (51%) and IV in 10 (26%). It is concluded from this series that clinical aspects and histological pattern in children Burkitt lymphoma in Cameroon are not different from what is observed in other endemic areas.
ISSN:0007-4551