The evaluation of antigens and antisera for their use in the serodiagnosis of aspergillosis

Aspergillosis became an important opportunistic mycosis during the last years, with a great variety of clinical manifestations. To contribute to the replenishing of this mycosis serodiagnosis, biologic reactives (antigens and antisera) were prepared from strains of the species Aspergillus niger, Asp...

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Bibliographic Details
Published inRevista cubana de medicina tropical Vol. 47; no. 2; pp. 118 - 121
Main Authors Fernández Andreu, C M, Travieso Ruiz, F, Martínez Machín, G, Perurena Lancha, M
Format Journal Article
LanguageSpanish
Published Cuba 1995
Subjects
Animals
Antigens, Fungal - isolation & purification
Aspergillosis - diagnosis
Aspergillus flavus - immunology
Aspergillus niger - immunology
Humans
Immune Sera - isolation & purification
Immunization
Precipitin Tests - methods
Rabbits
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Summary:Aspergillosis became an important opportunistic mycosis during the last years, with a great variety of clinical manifestations. To contribute to the replenishing of this mycosis serodiagnosis, biologic reactives (antigens and antisera) were prepared from strains of the species Aspergillus niger, Aspergillus flavus and Aspergillus terreus for their use in immunoprecipitation assays. The reactives were assessed by double immunospreading versus a reference commercial system; satisfactory results were obtained, and this guarantees the widening of the aspergillosis serodiagnosis in the Mycology Laboratory of the "Pedro Kourí" the Tropical Medicine Institute (IPK) with important imports savings.
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ISSN:0375-0760