Mechanism of potentiation of contraction in glycerol-treated muscles

The glycerol was shown to lead to a considerable though transient increase in the contractile amplitude of the m. sartorius. Prolonged incubation of the muscle in the Ringer and Ca-free solutions in presence of glycerol led to a decrease in the response following potentiation. The potentiation due t...

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Bibliographic Details
Published inT͡S︡itologii͡a Vol. 17; no. 1; p. 46
Main Authors Pak, A D, Esyrev, O V
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.1975
Subjects
Animals
Anura
Calcium - physiology
Glycerol - pharmacology
In Vitro Techniques
Muscle Contraction - drug effects
Stimulation, Chemical
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Summary:The glycerol was shown to lead to a considerable though transient increase in the contractile amplitude of the m. sartorius. Prolonged incubation of the muscle in the Ringer and Ca-free solutions in presence of glycerol led to a decrease in the response following potentiation. The potentiation due to glycerol seems to be caused by Ca2+ release which, in its turn, is due to the glycerol effect on membranes of SR and T-systems.
ISSN:0041-3771