Use of water-organic systems in the enzymatic transformation of steroids

This review surveys existing data on the use of water-organic systems, one of the promising methods of enzymic transformation of steroids. The procedures for reducing the inhibitory effect of solvents on enzymes and microbial cells are discussed. It is shown that hydrophobic capacity of gels and sub...

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Bibliographic Details
Published inPrikladnaja biohimija i mikrobiologija Vol. 19; no. 1; p. 20
Main Authors Arinbasarova, A Iu, Koshcheenko, K A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.1983
Subjects
Bacteria - enzymology
Biotransformation
Chemistry, Pharmaceutical
Enzymes - pharmacology
Gels
Solutions
Solvents - pharmacology
Steroids - pharmacology
Substrate Specificity
Surface-Active Agents - pharmacology
Water - pharmacology
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Summary:This review surveys existing data on the use of water-organic systems, one of the promising methods of enzymic transformation of steroids. The procedures for reducing the inhibitory effect of solvents on enzymes and microbial cells are discussed. It is shown that hydrophobic capacity of gels and substrates, polarity of solvents, and coefficients of the distribution of reaction components between phases are to be taken into consideration when performing steroid transformation in the presence of organic solvents in order to increase its efficiency.
ISSN:0555-1099