Evaluation and problems of second-look operations in resectable gastric cancer

• Published in: Gan to kagaku ryoho Vol. 16; no. 4 Pt 2-2; p. 1295
• Main Authors: Niimoto, M, Jinushi, K, Kirihara, Y, Yamamoto, T, Kuninobu, H, Saeki, T, Yanagawa, E, Toge, T, Hattori, T
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.04.1989
• Subjects: Antineoplastic Agents - therapeutic use; Combined Modality Therapy; Drug Screening Assays, Antitumor; Evaluation Studies as Topic; Gastrectomy; Humans; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Lymph Node Excision; Lymphatic Metastasis; Neoplasm Recurrence, Local - surgery; Peritoneal Neoplasms - secondary; Peritoneal Neoplasms - surgery; Prognosis; Recurrence; Reoperation; Stomach Neoplasms - drug therapy; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery
• ISSN: 0385-0684

During the period from June 1973 to December 1985, one thousand and ninety-seven patients with primary gastric cancer have been operated on in our Dept. of Surgery. Of the 1097 gastric cancer patients, 59 were reoperated and evaluated for chemotherapeutic effects. The cases were 21/548 (3.83%) for absolute curatively resection, 16/202 (7.92%) for relative curatively resection, 9/64 (14.0%) for relatively noncurative resection and 13/283 (4.59%) for absolutely noncurative resection, respectively, The median survival period from primary gastrectomy to second look operation was less than 2 years, and the prognoses were not very good. The factors of relaparotomy were peritoneal dissemination 44/59 (78.6%), invasion to contiguous structures, lymph node metastases and liver metastasis. Those with local recurrence or remnant stomach cancer could be resected in 5 cases, and one patient was well more than 2 years following surgery. The reoperation procedures were reconstruction of artificial anus, intestinal anastomosis or intestinal fistula. Some 7 of 59 patients were found to be entirely beyond surgical aid at the second look operation and were administered large-dose OK-432 or ADM patch method. These methods are suggested for their usefulness for peritoneal dissemination.