Thromboembolism prophylaxis in pregnancy and labor

Oral anticoagulants are contraindicated during pregnancy, especially during the I and III trimester, therefore heparin is recommended instead. We used fraxiparine s.c. once daily in prophylactic doses in 6 patients during pregnancy and labor (mean time of prophylaxis 6.5 months). Two of them receive...

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Bibliographic Details
Published inGinekologia polska Vol. 67; no. 11; p. 548
Main Author Czestochowska, E
Format Journal Article
LanguagePolish
Published Poland 01.11.1996
Subjects
Anticoagulants - therapeutic use
Drug Administration Schedule
Female
Heart Valve Prosthesis
Hemostasis - drug effects
Humans
Nadroparin - therapeutic use
Pregnancy
Pregnancy Complications, Cardiovascular - blood
Pregnancy Complications, Cardiovascular - prevention & control
Pregnancy Outcome
Thromboembolism - blood
Thromboembolism - prevention & control
Thrombophlebitis - blood
Thrombophlebitis - prevention & control
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Summary:Oral anticoagulants are contraindicated during pregnancy, especially during the I and III trimester, therefore heparin is recommended instead. We used fraxiparine s.c. once daily in prophylactic doses in 6 patients during pregnancy and labor (mean time of prophylaxis 6.5 months). Two of them received fraxiparine because of mechanical valve prosthesis, four after deep venous thrombosis occurring during the first few weeks of pregnancy. The pregnancies were uneventful, thromboembolic or haemorrhagic complications during delivery did not occur. Newborns were healthy, disturbances of hemostasis were not observed.
ISSN:0017-0011