Calcium ions in the life cycle of Streptomyces albogriseolus 444

The influence of Ca2+ on the growth, antibiotic production and differentiation of Streptomyces albogriseolus 444 was studied. Consumption of the calcium ions by the strain was followed up. It was shown that Ca2+ changed the dynamics of the biomass accumulation and had no significant effect on the an...

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Bibliographic Details
Published inAntibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] Vol. 42; no. 4; p. 12
Main Authors Danova, S T, Moncheva, P A, Antonova, S K, Ivanova, I V
Format Journal Article
LanguageRussian
Published Russia (Federation) 1997
Subjects
Anti-Bacterial Agents - biosynthesis
Anti-Bacterial Agents - pharmacology
Calcium - physiology
Nigericin - biosynthesis
Nigericin - pharmacology
Streptomyces - drug effects
Streptomyces - growth & development
Streptomyces - physiology
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Summary:The influence of Ca2+ on the growth, antibiotic production and differentiation of Streptomyces albogriseolus 444 was studied. Consumption of the calcium ions by the strain was followed up. It was shown that Ca2+ changed the dynamics of the biomass accumulation and had no significant effect on the antibiotic production. Calcium present in the medium was assimilated more intensively during the first 24 hours of the strain growth. The own antibiotic nigericin exogenously added to the medium increased the calcium assimilation. In the presence of Ca2+ the nigericin stimulation of the strain differentiation was higher.
ISSN:0235-2990