Correction of immunologic disorders in patients with burns

Addition of immunomodulating therapy with Thymalin, a thymus agent, to the multimodality therapy of burnt patients contributes to a rapid normalization of immunological parameters. The most marked immune response was observed 7-10 days after a therapy course initiated in the early periods of burn di...

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Bibliographic Details
Published inHirurgija (Moskva) no. 2; p. 116
Main Authors Shkrob, L O, Lukoianova, T N, Vishnevskaia, S M, Panova, Iu M, Kashin, Iu D
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.02.1990
Subjects
Adjuvants, Immunologic
Adolescent
Adult
Aged
Blood Transfusion
Burns - immunology
Burns - therapy
Combined Modality Therapy
Humans
Leukocyte Count
Lymphopenia - etiology
Lymphopenia - immunology
Lymphopenia - therapy
Middle Aged
T-Lymphocytes - immunology
Thymus Hormones - therapeutic use
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Summary:Addition of immunomodulating therapy with Thymalin, a thymus agent, to the multimodality therapy of burnt patients contributes to a rapid normalization of immunological parameters. The most marked immune response was observed 7-10 days after a therapy course initiated in the early periods of burn disease in patients with severely depressed T-system immunity and a high sensitivity to the drug. Inclusion of a donor blood leukomass transfusion course activates the cellular link of the immune system just after the treatment course, but fails to favour a stable normalization of thymus-dependent lymphocyte ratios.
ISSN:0023-1207