The expression of antigens, detectable with ICO-series monoclonal antibodies, on the surfaces of cells forming granulocyte and macrophage colonies in semiliquid agar

• Published in: Eksperimentalʹnaja onkologija Vol. 11; no. 1; p. 46
• Main Authors: Savel'eva, E V, Kharlamova, L A, Baryshnikov, A Iu, Agafonov, V A, Tupitsyn, N N
• Format: Journal Article
• Language: Russian
• Published: Ukraine 1989
• Subjects: Agar; Antibodies, Monoclonal - immunology; Antigens, Differentiation - analysis; Antigens, Surface - analysis; Bone Marrow - immunology; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Complement System Proteins - immunology; Granulocytes - immunology; Humans; Macrophages - immunology; Stem Cells - immunology

The expression of antigens on granulocyte-macrophagal colony-forming cells of patients with nonhematological diseases was studied. Treatment of bone marrow cells with murine monoclonal antibodies ICO-1 and ICO-11 led to statistically significant inhibition of the number of growing colonies. Monoclon...