Combination of the sieve effect and ion exchange chromatography during isolation of recombinant alpha2-interferon on the cellosorbent CS KU-23
Preliminary purification of alpha 2-interferon from the culture liquid on cation-exchange sorbents was studied. Application of a cellosorbent based on the cationite KU-23 resulted in a 20-25-fold purification of recombinant alpha 2-interferon in a one-step process as a result of combination of the s...
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Published in | Prikladnaja biohimija i mikrobiologija Vol. 33; no. 1; p. 28 |
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Main Authors | , , , |
Format | Journal Article |
Language | Russian |
Published |
Russia (Federation)
01.01.1997
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Subjects | |
Online Access | Get more information |
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Summary: | Preliminary purification of alpha 2-interferon from the culture liquid on cation-exchange sorbents was studied. Application of a cellosorbent based on the cationite KU-23 resulted in a 20-25-fold purification of recombinant alpha 2-interferon in a one-step process as a result of combination of the sieve effect and ion-exchange chromatography. |
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ISSN: | 0555-1099 |