Factors determining the development of wound infection after appendectomy

In order to illustrate which factors are of significance for the development of wound infection after appendectomy, an extensive prospective material of 2,097 patients submitted to appendectomy was analysed. Regression analyses demonstrated that age alone, employment of preoperative antibiotics (cef...

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Bibliographic Details
Published inUgeskrift for læger Vol. 152; no. 3; p. 157
Main Authors Vennits, B P, Bauer, T, Hahn-Pedersen, J, Galatius, H, Lysen, D, Holm, B, Kristensen, E S, Graversen, P H, Wilhelmsen, F S, Skjoldborg, H
Format Journal Article
LanguageDanish
Published Denmark 15.01.1990
Subjects
Adolescent
Adult
Age Factors
Aged
Anti-Bacterial Agents - administration & dosage
Appendectomy - adverse effects
Female
Humans
Male
Middle Aged
Premedication
Prospective Studies
Surgical Wound Infection - etiology
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Summary:In order to illustrate which factors are of significance for the development of wound infection after appendectomy, an extensive prospective material of 2,097 patients submitted to appendectomy was analysed. Regression analyses demonstrated that age alone, employment of preoperative antibiotics (cefoxitin) and patient delay (time from onset of symptoms till admission) were of significance. The present authors conclude, on the basis of this material, that all patients over 25 years of age should be given preoperative antibiotic prophylaxis which covers aerobic and also anaerobic microorganisms. If a gangrenous or perforated appendix is found, antibiotics should be administered intraoperatively if prophylactic treatment has not been administered. In cases of perforation, antibiotics should be administered postoperatively for 72 hours.
ISSN:0041-5782