Changes in the neural activity of the blood serum from patients with ischemic heart disease

• Published in: Biulleten' eksperimental'noi biologii i meditsiny Vol. 116; no. 8; p. 161
• Main Authors: Azbel', D I, Zapara, T A, Kuznetsova, I Iu, Ratushniak, A S, Shergin, S M, Shurgaia, A M, Shtark, M B
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.08.1993
• Subjects: Animals; Blood - radiation effects; Humans; Laser Therapy; Lymnaea; Membrane Potentials - drug effects; Membrane Potentials - physiology; Myocardial Ischemia - blood; Myocardial Ischemia - radiotherapy; Neurons - drug effects; Neurons - physiology
• ISSN: 0365-9615

The isolated neurons of snail (Lymnaea stagnalis) were as test object for the evaluation of the blood serum neuroactivity. The blood serum was tested before treatment and after six applications of intravenous laser therapy (ILT). All blood serum specimens produced depolarization of the cell membrane potential. The quantitative comparison of membrane toxicity of control and experimental blood serum specimens permitted to divide the patients into three groups. Blood serum (after six applications of ILT of patients from the first and second groups produced a lower membrane toxicity effect on neurons. In the groups the membrane toxicity effect decrease by 43% +/- 10.3 and 7.3 +/- 2.2% respectively. In third group the membrane toxicity effect increased by 21.5 +/- 4.5. All patients from the third group had myocardial infarction less than one year before being given a course on the treatment. The ILT was found to be able to decrease the activity of the blood serum components disrupting normal functioning of the ionic mechanisms of cell membranes.