Circulating immune complex cholesterol as a biochemical marker of coronary atherosclerosis

The study was undertaken to examine 134 patients who were divided into 2 groups: 1) those with angiographically documented coronary atherosclerosis and 2) those with unaltered coronary arteries. The levels of immune complex cholesterol and the parameters of serum lipid spectrum were investigated in...

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Bibliographic Details
Published inKardiologiia Vol. 31; no. 2; p. 42
Main Authors Kalenich, O S, Tertov, V V, Novikov, I D, Vorob'eva, E G, Perova, N V, Metel'skaia, V A, Pomerantsev, E V, Liakishev, A A, Ruda, M Ia, Orekhov, A N
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.02.1991
Subjects
Adult
Aged
Antigen-Antibody Complex - analysis
Apolipoproteins A - analysis
Apolipoproteins B - analysis
Biomarkers
Cholesterol - analysis
Coronary Disease - diagnosis
Coronary Disease - immunology
Female
Humans
Immunoelectrophoresis
Male
Middle Aged
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Summary:The study was undertaken to examine 134 patients who were divided into 2 groups: 1) those with angiographically documented coronary atherosclerosis and 2) those with unaltered coronary arteries. The levels of immune complex cholesterol and the parameters of serum lipid spectrum were investigated in all the patients. The level of immune complex cholesterol and the apo B/apo AI ratio were the most informative indices in the characterization of coronary atherosclerosis. Immune complex cholesterol may be used as a marker of coronary atherosclerosis, the diagnostic accuracy is 78% with this method.
ISSN:0022-9040