Short-duration fatty meal loading for the assessment of intestinal malabsorption syndromes in children: preliminary study

The determination of fecal fat gives a reliable index for studying fat intestinal absorption in children, but requires the collection of whole day stools for 3 consecutive days. To avoid stool collection constraint, the authors implemented a 3-point short-duration fatty meal test with determination...

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Bibliographic Details
Published inPédiatrie (Paris ) Vol. 47; no. 2; p. 141
Main Authors Koki Ndombo, P O, Nko'o Amvene, S, Brechot, J F, Garrigue, M A, Ndam Ndjitoyap, C E, Maurage, C, Malonga, E, Rolland, J C
Format Journal Article
LanguageFrench
Published France 1992
Subjects
Administration, Oral
Adolescent
Child
Child, Preschool
Chylomicrons - blood
Dietary Fats - administration & dosage
Dietary Fats - pharmacology
Female
Humans
Infant
Malabsorption Syndromes - blood
Malabsorption Syndromes - epidemiology
Male
Prospective Studies
Time Factors
Triglycerides - blood
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Summary:The determination of fecal fat gives a reliable index for studying fat intestinal absorption in children, but requires the collection of whole day stools for 3 consecutive days. To avoid stool collection constraint, the authors implemented a 3-point short-duration fatty meal test with determination of subsequent increase in serum levels of triglycerides and chylomicrons which then were compared to fasting values. Normal values were determined among control healthy children. Five patients with diagnosed malabsorption syndromes showed markedly impaired results. This fatty meal test seemed simple, easy to perform during a full-day admission. Further studies are being implemented to confirm its good diagnostic value.
ISSN:0031-4021