The effect of activating agents on the membrane potential of lymphocytes in hypertension patients

Changes of membrane potential of lymphocytes of peripheral blood under the influence of the activation agents: phytohemagglutinin, concanavalin A and Ca(2+)-ionophore A 23187 in 25 patients (men) with hypertensive disease and 8 healthy persons (men) aged 25 to 35 years have been studied. The results...

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Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 115; no. 2; p. 151
Main Authors Malaia, L T, Koval', S N, Brovkovich, V M, Kurilo, N B
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.02.1993
Subjects
Adult
Calcimycin - pharmacology
Concanavalin A - pharmacology
Humans
Hypertension - blood
Hypertension - physiopathology
Lymphocyte Activation
Lymphocytes - cytology
Lymphocytes - drug effects
Male
Membrane Potentials - drug effects
Phytohemagglutinins - pharmacology
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Summary:Changes of membrane potential of lymphocytes of peripheral blood under the influence of the activation agents: phytohemagglutinin, concanavalin A and Ca(2+)-ionophore A 23187 in 25 patients (men) with hypertensive disease and 8 healthy persons (men) aged 25 to 35 years have been studied. The results obtained testify to the existence of functional disturbances of lymphocytes' membrane and confirmed the wide-spread of the membrane defect in patients with hypertensive disease.
ISSN:0365-9615