Clinical manifestations and the problems of classification of HIV infection

The clinical manifestations and some immunological parameters (CD4 lymphocytes, CD4/CD8 ratio, IgM, IgA, IgG levels, skin test) were examined in 226 adult patients (148 males and 78 females) infected with HIV. These included 58 (26%) asymptomatic patients with seropositive test, 109 (48%) with the o...

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Published inVestnik Rossiĭskoĭ akademii medits︠i︡nskih nauk no. 9-10; p. 16
Main Authors Iurin, O G, Irova, T I, Gabrilovich, D I, Suvorova, Z K, Kravchenko, A V, Potekaev, N S, Kharchenko, O I, Pokrovskiĭ, V V
Format Journal Article
LanguageRussian
Published Russia (Federation) 1992
Subjects
Acquired Immunodeficiency Syndrome - classification
Acquired Immunodeficiency Syndrome - diagnosis
Acquired Immunodeficiency Syndrome - immunology
Adult
Aged
AIDS Serodiagnosis - methods
CD4-CD8 Ratio
Female
HIV Infections - diagnosis
HIV Infections - immunology
Humans
Immunoglobulins - analysis
Leukocyte Count
Male
Middle Aged
Severity of Illness Index
T-Lymphocytes - immunology
T-Lymphocytes - pathology
Time Factors
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Summary:The clinical manifestations and some immunological parameters (CD4 lymphocytes, CD4/CD8 ratio, IgM, IgA, IgG levels, skin test) were examined in 226 adult patients (148 males and 78 females) infected with HIV. These included 58 (26%) asymptomatic patients with seropositive test, 109 (48%) with the only clinical manifestation generalized lymphadenopathy; 54 (24%) with AIDS-related infections, 5 (2%) with AIDS. A subsequent follow-up of 3 months to 3 years demonstrated that AIDS developed in 7 patients, 9 died. The period of infection with HIV and death ranged from 1.5 to 9 years. The signs of cell immunodeficiency were found in 70% of the examinees. Recommendations are given on the classification of HIV infection.
ISSN:0869-6047