Field trial of praziquantel in human opisthorchiasis in Thailand

Praziquantel is an excellent drug for treatment against Opisthorchis viverrini infection. Sixty cases of Opisthorchis viverrini infection were treated with Praziquantel, 3 x 25 mg/kg body weight for one day, except one case that was retreated with the same regimen at one month after the first treatm...

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Bibliographic Details
Published inSoutheast Asian journal of tropical medicine and public health Vol. 12; no. 4; p. 598
Main Authors Supanvanich, S, Supanvanich, K, Pawabut, P
Format Journal Article
LanguageEnglish
Published Thailand 01.12.1981
Subjects
Administration, Oral
Humans
Isoquinolines - therapeutic use
Opisthorchiasis - drug therapy
Praziquantel - administration & dosage
Praziquantel - adverse effects
Praziquantel - therapeutic use
Thailand
Thailand
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Summary:Praziquantel is an excellent drug for treatment against Opisthorchis viverrini infection. Sixty cases of Opisthorchis viverrini infection were treated with Praziquantel, 3 x 25 mg/kg body weight for one day, except one case that was retreated with the same regimen at one month after the first treatment, and the cure rate was 100.0% at one year after the treatment. The side effects of the drug were headache, lassitude, sleepiness, and diarrhoea, but most of these were only in mild degree. Other laboratory findings showed no abnormal changes.
ISSN:0125-1562